Unlike heart disease, stroke is more of a heterogeneous disease that includes cerebral hemorrhages and several pathogenic subtypes of ischemic stroke. 2 Notably, important differences between MI and stroke warrant definitions of these 2 entities that are somewhat overlapping yet also distinct, and the universal definition of MI cannot fully apply to the approach to stroke. * The writing group was composed of experts in neurology, neurosurgery, neuroradiology, neuropathology, clinical research methods, epidemiology, biomarkers, policy, and global public health.Ī similar approach has been used to generate a multisocietal universal definition of myocardial infarction (MI). The leadership of the AHA/ASA reached out to colleagues from the American Academy of Neurology, the American Association of Neurological Surgeons and Congress of Neurological Surgeons, the US Food and Drug Administration, the US Centers for Disease Control and Prevention, the National Institute of Neurological Disorders and Stroke, and others to establish a universal definition of stroke based on the current understanding of pathophysiology, as well as implications for clinical practice, research, and public policy. 1 Classic definitions of stroke are decades old and have become outdated, but modern definitions have not been formalized and officially adopted by the AHA, ASA, or any other major organization.
#Per ty seriali maria e antonio update
The Stroke Council of the American Heart Association (AHA)/American Stroke Association (ASA) published a scientific statement in 2009 to update and clarify the definition of transient ischemic attack (TIA), which in turn requires a reevaluation of the broader definition of stroke.
Advances in basic science, neuropathology, and neuroimaging have improved the understanding of ischemia, infarction, and hemorrhage in the CNS. Despite its global impact, the term “stroke” is not consistently defined in clinical practice, in clinical research, or in assessments of the public health. Stroke is classically characterized as a neurological deficit attributed to an acute focal injury of the central nervous system (CNS) by a vascular cause, including cerebral infarction, intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH), and is a major cause of disability and death worldwide. The updated definition of stroke incorporates clinical and tissue criteria and can be incorporated into practice, research, and assessments of the public health. Stroke also broadly includes intracerebral hemorrhage and subarachnoid hemorrhage. Central nervous system infarction occurs over a clinical spectrum: Ischemic stroke specifically refers to central nervous system infarction accompanied by overt symptoms, while silent infarction by definition causes no known symptoms. Central nervous system infarction is defined as brain, spinal cord, or retinal cell death attributable to ischemia, based on neuropathological, neuroimaging, and/or clinical evidence of permanent injury. The Stroke Council of the American Heart Association/American Stroke Association convened a writing group to develop an expert consensus document for an updated definition of stroke for the 21st century. The classic definition is mainly clinical and does not account for advances in science and technology. , MDon behalf of the American Heart Association Stroke Council, Council on Cardiovascular Surgery and Anesthesia, Council on Cardiovascular Radiology and Intervention, Council on Cardiovascular and Stroke Nursing, Council on Epidemiology and Prevention, Council on Peripheral Vascular Disease, and Council on Nutrition, Physical Activity and Metabolismĭespite the global impact and advances in understanding the pathophysiology of cerebrovascular diseases, the term “stroke” is not consistently defined in clinical practice, in clinical research, or in assessments of the public health.
Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB).
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